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Article

No evidence of selection for mutational robustness during lethal mutagenesis of lymphocytic choriomeningitis virus.

Virology - 15 Aug 2008

Martín Verónica, Grande-Pérez Ana, Domingo Esteban

Abstract excerpt

Lethal mutagenesis is a transition towards virus extinction mediated by enhanced mutation rates during viral genome replication. Theoretical studies suggest that viruses can evolve towards regions of their fitness landscapes at which they display resistance to the deleterious effects of mutations. It has been suggested that such mutational robustness could jeopardize lethal mutagenesis. We have used the...

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Identifiers

PMID: 18572218
DOI: 10.1016/j.virol.2008.05.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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