Article
RASD2, MYH9, and CACNG2 genes at chromosome 22q12 associated with the subgroup of schizophrenia with non-deficit in sustained attention and executive function.
Biological psychiatry - 1 Nov 2008
Liu Yu-Li, Fann Cathy Shen-Jang, Liu Chih-Min, Chen Wei J, Wu Jer-Yuarn, Hung Shuen-Iu, Chen Chun-Houh, Jou Yuh-Shan, Liu Shi-Kai, Hwang Tzung-Jeng, Hsieh Ming H, Chang Chien Ching, Yang Wei-Chih, Lin Jin-Jia, Chou Frank Huang-Chih, Faraone Stephen V, Tsuang Ming T, Hwu Hai-Gwo
Abstract excerpt
BACKGROUND: In a previous linkage study of schizophrenia that included Taiwanese samples, the marker D22S278 (22q12.3) was significantly linked to schizophrenia (p = .001). METHODS: We conducted fine mapping of the implicated genomic region, with 47 validated single nucleotide polymorphism (SNP) markers around 1 Mb of D22S278, in a Taiwanese sample of 218 pedigrees with at least 2 siblings affected with...
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