Article
PON1 polymorphisms can predict generalized anxiety and depressed mood in patients with multiple chemical sensitivity.
Personalized medicine - 1 May 2021
Mosca Alessio, Del Casale Antonio, Borro Marina, Gentile Giovanna, Pomes Leda Marina, Padovano Alessio, Fiaschè Federica, Pinzone Vito, Rapinesi Chiara, Zoppi Teodolinda, Brugnoli Roberto, Sani Gabriele, Kotzalidis Georgios Demetrios, Girardi Paolo, Ferracuti Stefano, Simmaco Maurizio, Pompili Maurizio
Abstract excerpt
Background: Multiple chemical sensitivity (MCS) is a chronic condition with somatic, cognitive and affective symptoms that follow contact with chemical agents at usually non toxic concentrations. We aimed to assess the role of genetic polymorphisms involved in oxidative stress on anxiety and depression in MCS. Materials & methods: Our study investigated the CAT rs1001179, MPO rs2333227, PON1 rs662 and PON1...
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