Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The chemical defensive system in the pathobiology of idiopathic environment-associated diseases.

Current drug metabolism - 1 Oct 2009

Korkina L, Scordo M G, Deeva I, Cesareo E, De Luca C

Abstract excerpt

Chemical defensive system consisting of bio-sensoring, transmitting, and responsive elements has been evolved to protect multi-cellular organisms against environmental chemical insults (xenobiotics) and to maintain homeostasis of endogenous low molecular weight metabolites (endobiotics). Both genetic and epigenetic defects of the system in association with carcinogenesis and individual sensitivity to anti-tumor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Expression Regulation, Enzymologic
Share to Inactivation, Metabolic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lupus Erythematosus, Systemic

Share to Models, Biological

Share to Oxidative Stress

Share to Peroxides

Share to Vitiligo

Share to Xenobiotics

Source

Identifiers

PMID: 20201826
DOI: 10.2174/138920009790274568

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The chemical defensive system in the pathobiology of idiopathic environment-associated diseases.PMID 20201826Read ↗

The Search for Reliable Biomarkers of Disease in Multiple Chemical Sensitivity and Other Environmental IntolerancesSemantic proximity Read ↗

Detoxification enzymes: cellular metabolism and susceptibility to various diseases.Semantic proximity Read ↗

Hallmarks of environmental insults.Semantic proximity Read ↗

A Proposal for Clinical Biomarkers in Multiple Chemical Sensitivity.Semantic proximity Read ↗

Xenobiotic sensor- and metabolism-related gene variants in environmental sensitivity-related illnesses: a survey on the Italian population.Semantic proximity Read ↗

MECHANISMS IN ENDOCRINOLOGY: Update on pathogenesis of primary adrenal insufficiency: beyond steroid enzyme deficiency and autoimmune adrenal destructionSemantic proximity Read ↗

Toxicogenomics and clinical toxicology: an example of the connection between basic and applied sciences.Semantic proximity Read ↗

The Human Glyoxalase Gene Family in Health and DiseaseSemantic proximity Read ↗

Genomics of Detoxification: How Genomics can be Used for Targeting Potential Intervention and Prevention Strategies Including Nutrition for Environmentally Acquired Illness.Semantic proximity Read ↗

Unbiased Approach for the Identification of Molecular Mechanisms Sensitive to Chemical ExposuresSemantic proximity Read ↗

GENOMIC, TRANSCRIPTOMIC AND PROTEOMIC TECHNOLOGIES AS A MODERN TOOL FOR HEALTH DISORDERS DIAGNOSTICS, ASSOCIATED WITH THE IMPACT OF ENVIRONMENTAL FACTORSSemantic proximity Read ↗

Evaluation of genetic polymorphisms in patients with multiple chemical sensitivity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.