Early separation of B and T lymphocyte precursors in chick embryo.

doi:10.1084/jem.174.2.397

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Article

Early separation of B and T lymphocyte precursors in chick embryo.

The Journal of experimental medicine - 1 Aug 1991

Houssaint E, Mansikka A, Vainio O

Abstract excerpt

Embryonic chimeras were used to demonstrate an early separation of chicken T and B cell precursors. Genetically polymorphic cell surface antigens, Bu-1 and Ov, which are expressed on cells of the B and T lineage, respectively, are useful markers in adoptive cell transfer studies. Allelic products Bu-1a and Bu-1b can be detected with monoclonal antibodies (mAbs) L22 and 11G2, respectively, and the Ov antigen with...

Topics

Alleles
Animals
Antibodies, Monoclonal
Antigens, Surface
B-Lymphocytes
Base Sequence
Cell Differentiation
Chick Embryo
Chickens
Chimera
DNA
Fluorescent Antibody Technique

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Rearrangement, B-Lymphocyte, Light Chain

Immunoenzyme Techniques

Lymphoid Tissue

Molecular Sequence Data

Oligonucleotide Probes

Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 1856628
DOI: 10.1084/jem.174.2.397
PMCID: PMC2118911

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1856628-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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