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Article

Early separation of B and T lymphocyte precursors in chick embryo.

The Journal of experimental medicine - 1 Aug 1991

Houssaint E, Mansikka A, Vainio O

Abstract excerpt

Embryonic chimeras were used to demonstrate an early separation of chicken T and B cell precursors. Genetically polymorphic cell surface antigens, Bu-1 and Ov, which are expressed on cells of the B and T lineage, respectively, are useful markers in adoptive cell transfer studies. Allelic products Bu-1a and Bu-1b can be detected with monoclonal antibodies (mAbs) L22 and 11G2, respectively, and the Ov antigen with...

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Identifiers

PMID: 1856628
DOI: 10.1084/jem.174.2.397
PMCID: PMC2118911

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