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Article

The chicken B-cell receptor complex and its role in avian B-cell development.

Immunological reviews - 1 Jun 2000

Sayegh C E, Demaries S L, Pike K A, Friedman J E, Ratcliffe M J

Abstract excerpt

The bursa of Fabricius is critical to normal B-lymphocyte development in birds. During embryonic life, B-cell precursors migrate to the bursal rudiment and those which have undergone productive V(D)J recombination colonize lymphoid follicles and undergo immunoglobulin V gene diversification by gene conversion. The chicken surface IgM complex appears structurally and functionally equivalent to its mammalian...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Gene Rearrangement, B-Lymphocyte

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Share to Receptors, Antigen, B-Cell

Source

Identifiers

PMID: 10933603

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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