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Article

Bone matrix formation in osteogenic cultures derived from human embryonic stem cells in vitro.

Stem cells and development - 1 Feb 2007

Kärner Elerin, Unger Christian, Sloan Alastair J, Ahrlund-Richter Lars, Sugars Rachael V, Wendel Mikael

Abstract excerpt

Bone matrix production and mineralization involves sophisticated mechanisms, including the initial formation of an organic extracellular matrix into which inorganic hydroxyapatite crystals are later deposited. Human embryonic stem (hES) cells offer a potential to study early developmental processes and provide an unlimited source of cells. In this study, four different hES cell lines were used, and two different...

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Identifiers

PMID: 17233553
DOI: 10.1089/scd.2006.0010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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