Enhanced Derivation of Osteogenic Cells from Murine Embryonic Stem Cells After Treatment with HepG2- Conditioned Medium and Modulation of the Embryoid Body Formation Period: Application to Skeletal Tissue Engineering

Abstract excerpt

Despite the considerable progress made in directing embryonic stem cell (ESC) differentiation to therapeutically useful lineages, several issues remain to be resolved before ESCs can be used for cell therapy: 1) increasing the efficiency of specific lineage generation, and 2) developing time- and cost-effective culture systems for controlling ESC differentiation. Our study aimed to develop efficient methods to...

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