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Differentiation of Human Induced Pluripotent Stem Cells (hiPSCs) into Osteoclasts

1 Jan 2020

Abstract excerpt

Defects in bone resorption by osteoclasts result in numerous rare genetic bone disorders as well as in some common diseases such as osteoporosis or osteopetrosis. The use of hiPSC-differentiated osteoclasts opens new avenues in this research field by providing an unlimited cell source and overcoming obstacles such as unavailability of human specimens and suitable animal models. Generation of hiPSCs is well...

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PMID: 33659501
DOI: 10.21769/bioprotoc.3854

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