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Article

Hypermutation of an ancient human retrovirus by APOBEC3G.

Journal of virology - 1 Sept 2008

Lee Young Nam, Malim Michael H, Bieniasz Paul D

Abstract excerpt

Human endogenous retroviruses (HERVs) comprise approximately 8% of the human genome, but all are remnants of ancient retroviral infections and harbor inactivating mutations that render them replication defective. Nevertheless, as viral "fossils," HERVs may provide insights into ancient retrovirus-host interactions and their evolution. Indeed, one endogenous retrovirus [HERV-K(HML-2)], which has replicated in...

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Identifiers

PMID: 18562521
DOI: 10.1128/JVI.00751-08
PMCID: PMC2519637

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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