Article
The Aeromonas hydrophila cphA gene: molecular heterogeneity among class B metallo-beta-lactamases.
Journal of bacteriology - 1 Aug 1991
Massidda O, Rossolini G M, Satta G
Abstract excerpt
An Aeromonas hydrophila gene, named cphA, coding for a carbapenem-hydrolyzing metallo-beta-lactamase, was cloned in Escherichia coli by screening an Aeromonas genomic library for clones able to grow on imipenem-containing medium. From sequencing data, the cloned cphA gene appeared able to code for a polypeptide of 254 amino acids whose sequence includes a potential N-terminal leader sequence for targeting the...
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