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Article

Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora.

Antimicrobial agents and chemotherapy - 1 Jul 2008

Stoczko Magdalena, Frère Jean-Marie, Rossolini Gian Maria, Docquier Jean-Denis

Abstract excerpt

Metallo-beta-lactamases (MBLs) are zinc-dependent bacterial enzymes characterized by an efficient hydrolysis of carbapenems and a lack of sensitivity to commercially available beta-lactamase inactivators. Apart from the acquired subclass B1 enzymes, which exhibit increasing clinical importance and whose evolutionary origin remains unclear, most MBLs are encoded by resident genes found in the genomes of organisms...

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Identifiers

PMID: 18443127
DOI: 10.1128/AAC.01062-07
PMCID: PMC2443915

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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