Article
Interspecies comparisons of functional genetic variations and their implications in neuropsychiatry.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2009
Kas Martien J H, Gelegen Cigdem, Schalkwyk Leonard C, Collier David A
Abstract excerpt
Animal studies are important for the identification and functional characterization of the biological substrates underlying complex psychiatric disorders. However, novel insights into the relationship between the genome and behavior are needed for the development of fully valid translational models. Based on the notion that in different species, the same genes may independently give rise to alleles with similar...
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