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Stemness-related markers in cancer

1 Jan 2017

Abstract excerpt

Cancer stem cells (CSCs), with their self-renewal ability and multilineage differentiation potential, are a critical subpopulation of tumor cells that can drive tumor initiation, growth, and resistance to therapy. Like embryonic and adult stem cells, CSCs express markers that are not expressed in normal somatic cells and are thus thought to contribute towards a 'stemness' phenotype. This review summarizes the...

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PMID: 29276782
DOI: 10.4103/ctm.ctm_69_16

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