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Article

Role of PELP1/MNAR Signaling in Ovarian Tumorigenesis

15 Jun 2008

Abstract excerpt

Emerging evidence suggests that nuclear receptor (NR) coregulators have potential to act as master genes and their deregulation can promote oncogenesis. Proline-, glutamic acid-, and leucine-rich protein-1 (PELP1/MNAR) is a novel NR coregulator. Its expression is deregulated in hormone-driven cancers. However, the role of PELP1/MNAR in ovarian cancer progression remains unknown. Analysis of serial analysis of...

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PMID: 18559538
DOI: 10.1158/0008-5472.can-07-5698

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