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Estrogen regulates PDPK1 to promote cell proliferation in epithelial ovarian cancer

1 Nov 2024

Abstract excerpt

Epithelial ovarian cancer (EOC) is a common estrogen-sensitive tumor that poses a serious threat to women 's health, and the mortality rate of EOC ranks first among malignant tumors in females. Studies have indicated a strong link between estrogen abnormality and EOC progression. We accidently found that 3-phosphoinositide-dependent protein kinase-1 (PDPK1) is highly expressed in EOC tissues. Further, estrogen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39624293
DOI: 10.1016/j.heliyon.2024.e40296

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