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Article

Hypertrophic cardiomyopathy: from mutation to functional analysis of defective protein.

Croatian medical journal - 1 Jun 2011

Capek Pavel, Vondrasek Jiri, Skvor Jiri, Brdicka Radim

Abstract excerpt

AIM: To analyze the genesis of hypertrophic cardiomyopathy on a large cohort of patients from molecular genetics point of view and perform the functional analysis of the 3D molecular model of defective myosin-7 protein in silico. METHODS: The study enrolled 153 patients with diagnosed hypertrophic cardiomyopathy from different parts of the Czech Republic. DNA samples were analyzed for mutations in exons 21 and 22...

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Source

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Identifiers

PMID: 21674835
DOI: 10.3325/cmj.2011.52.384
PMCID: PMC3118724

Genes

MYH7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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