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Article

The human beta-myosin heavy chain gene: sequence diversity and functional characteristics of the protein.

Journal of cellular biochemistry - 14 Sept 2000

Wendel B, Reinhard R, Wachtendorf U, Zacharzowsky U B, Osterziel K J, Schulte H D, Haase H, Hoehe M R, Morano I

Abstract excerpt

The beta-myosin heavy chain gene (MYH7) encodes the motor protein that drives myocardial contraction. It has been proven to be a disease gene for hypertrophic cardiomyopathy (HCM). We analyzed the DNA sequence variation of MYH7 (about 16 kb) of eight individuals: six patients with HCM and two healthy controls. The overall DNA sequence identity was up to 97.2% compared to Jaenicke and coworkers (Jaenicke et al....

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Source

Identifiers

PMID: 10996847

Genes

MYH7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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