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Article

Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice.

American journal of physiology. Heart and circulatory physiology - 1 Aug 2008

Song Yanli, Coleman Laura, Shi Jianru, Beppu Hideyuki, Sato Kaori, Walsh Kenneth, Loscalzo Joseph, Zhang Ying-Yi

Abstract excerpt

Heterozygous bone morphogenetic protein receptor-II-knockout (BMPR2(+/-)) mice have a similar genetic trait like that in some idiopathic pulmonary arterial hypertension patients. To examine the effect of pulmonary endothelial injury in BMPR2(+/-) mice, we challenged the mice with two injections o...

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Share to Arachidonate 5-Lipoxygenase
Share to Bone Morphogenetic Protein Receptors, Type II

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hypertension, Pulmonary

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Share to Receptors, Transforming Growth Factor beta

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Source

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Identifiers

PMID: 18552156
DOI: 10.1152/ajpheart.91519.2007
PMCID: PMC2519229

Genes

BMPR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18552156-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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