Article
Imprinted disorders and growth.
Annales d'endocrinologie - 1 Jun 2017
Giabicani Éloïse, Brioude Frédéric, Le Bouc Yves, Netchine Irène
Abstract excerpt
Fetal growth is a complex process. Its restriction is associated with morbidity and long-term metabolic consequences. Imprinted genes have a critical role in mammalian fetal growth. Beckwith-Wiedemann syndrome (BWS) and Silver-Russell syndrome (SRS) are two imprinting disorders with opposite fetal growth disturbance. SRS is leading to severe fetal and postnatal growth retardation with severe feeding difficulties...
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