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Article

Genetic polymorphisms of GZMB and vitiligo: A genetic association study based on Chinese Han population.

Scientific reports - 29 Aug 2018

Xu Meifeng, Liu Yan, Liu Yale, Li Xiaoli, Chen Gang, Dong Wei, Xiao Shengxiang

Abstract excerpt

Vitiligo is a skin disease that affects 1% of the population worldwide. Both environmental and genetic factors contribute to the risk of vitiligo. GZMB encodes the enzyme Granzyme B, which plays an important role in cytotoxic T cell-induced apoptosis, and it has been considered one of the candidate genes for vitiligo because of its connections with human immune system. Overall, 3,120 study subjects with Chinese...

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Identifiers

PMID: 30158536
DOI: 10.1038/s41598-018-31233-8
PMCID: PMC6115438

Genes

GZMB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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