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Article

Functional polymorphisms in cell death pathway genes FAS and FAS ligand and risk of alopecia areata.

Archives of dermatological research - 1 Dec 2013

Kalkan Göknur, Ateş Omer, Karakuş Nevin, Sezer Saime

Abstract excerpt

FAS and FAS ligand (FASLG) are important proapoptotic proteins that have a significant function in regulating cell growth and apoptosis and play essential roles in many human autoimmune diseases. Alopecia areata (AA) is hypothesized to be an organ-specific autoimmune disease mediated by T cells to the hair follicles. The concept of an autoimmune mechanism as the basis for AA led us to investigate a possible...

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Identifiers

PMID: 23591741
DOI: 10.1007/s00403-013-1354-5

Genes

FAS
FASLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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