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Article

SMAD proteins control DROSHA-mediated microRNA maturation.

Nature - 3 Jul 2008

Davis Brandi N, Hilyard Aaron C, Lagna Giorgio, Hata Akiko

Abstract excerpt

MicroRNAs (miRNAs) are small non-coding RNAs that participate in the spatiotemporal regulation of messenger RNA and protein synthesis. Aberrant miRNA expression leads to developmental abnormalities and diseases, such as cardiovascular disorders and cancer; however, the stimuli and processes regul...

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Source

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Identifiers

PMID: 18548003
DOI: 10.1038/nature07086
PMCID: PMC2653422

Genes

DROSHA
SMAD4
DDX5
PDCD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18548003-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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