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Article

Genetic modifier screens reveal new components that interact with the Drosophila dystroglycan-dystrophin complex.

PloS one - 11 Jun 2008

Kucherenko Mariya M, Pantoja Mario, Yatsenko Andriy S, Shcherbata Halyna R, Fischer Karin A, Maksymiv Dariya V, Chernyk Yaroslava I, Ruohola-Baker Hannele

Abstract excerpt

The Dystroglycan-Dystrophin (Dg-Dys) complex has a capacity to transmit information from the extracellular matrix to the cytoskeleton inside the cell. It is proposed that this interaction is under tight regulation; however the signaling/regulatory components of Dg-Dys complex remain elusive. Understanding the regulation of the complex is critical since defects in this complex cause muscular dystrophy in humans....

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Identifiers

PMID: 18545683
DOI: 10.1371/journal.pone.0002418
PMCID: PMC2398783

Genes

EGFR

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