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Article

Dissecting muscle and neuronal disorders in a Drosophila model of muscular dystrophy.

The EMBO journal - 24 Jan 2007

Shcherbata Halyna R, Yatsenko Andriy S, Patterson Larissa, Sood Vanita D, Nudel Uri, Yaffe David, Baker David, Ruohola-Baker Hannele

Abstract excerpt

Perturbation in the Dystroglycan (Dg)-Dystrophin (Dys) complex results in muscular dystrophies and brain abnormalities in human. Here we report that Drosophila is an excellent genetically tractable model to study muscular dystrophies and neuronal abnormalities caused by defects in this complex. Using a fluorescence polarization assay, we show a high conservation in Dg-Dys interaction between human and Drosophila....

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Share to Adaptor Proteins, Signal Transducing
Share to Animals, Genetically Modified

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Polarity

Share to Dystroglycans

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Share to Muscular Dystrophy, Animal

Share to Nervous System Malformations

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Source

Open in PubMed Open full text

Identifiers

PMID: 17215867
DOI: 10.1038/sj.emboj.7601503
PMCID: PMC1783456

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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