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Article

Genetic variants of Clock transcription factor are associated with individual susceptibility to obesity.

The American journal of clinical nutrition - 1 Jun 2008

Sookoian Silvia, Gemma Carolina, Gianotti Tomas Fernández, Burgueño Adriana, Castaño Gustavo, Pirola Carlos Jose

Abstract excerpt

BACKGROUND: Altering circadian rhythmicity results in pathophysiologic changes resembling metabolic syndrome and fat accumulation. OBJECTIVE: We investigated the role of gene variants and derived haplotypes of the CLOCK transcription factor in obesity and related quantitative metabolic traits. DESIGN: Lean (n = 715) and overweight or obese (n = 391) unrelated subjects aged 34.4 +/- 8.6 y were included in a...

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Source

Identifiers

PMID: 18541547
DOI: 10.1093/ajcn/87.6.1606

Genes

CLOCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic variants of Clock transcription factor are associated with individual susceptibility to obesity.PMID 18541547Read ↗

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