Article
Circadian CLOCK gene polymorphisms in relation to sleep patterns and obesity in African Americans: findings from the Jackson heart study.
BMC genetics - 23 Jun 2017
Riestra Pia, Gebreab Samson Y, Xu Ruihua, Khan Rumana J, Gaye Amadou, Correa Adolfo, Min Nancy, Sims Mario, Davis Sharon K
Abstract excerpt
BACKGROUND: Circadian rhythms regulate key biological processes and the dysregulation of the intrinsic clock mechanism affects sleep patterns and obesity onset. The CLOCK (circadian locomotor output cycles protein kaput) gene encodes a core transcription factor of the molecular circadian clock influencing diverse metabolic pathways, including glucose and lipid homeostasis. The primary objective of this study was...
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