Article
Genetic association of the PERIOD3 (PER3) Clock gene with extreme obesity.
Obesity research & clinical practice - 1 Jan 2000
Azevedo Pedro Guimarães de, Miranda Luana Reis, Nicolau Eduardo Souza, Alves Rayane Benfica, Bicalho Maria Aparecida Camargos, Couto Patrícia Pereira, Ramos Adauto Versiani, Souza Renan Pedra de, Longhi Rafael, Friedman Eitan, Marco Luiz De, Bastos-Rodrigues Luciana
Abstract excerpt
BACKGROUND: Obesity has reached epidemic proportions worldwide, affecting life quality and span. Susceptibility to obesity is partly mediated by genetic differences. Indeed, several genes from the clock gene family have already been shown to be intimately associated with obesity in diverse ethnic groups. In the present study, an association between BMI and the rs707467, rs228697 and rs228729 PER3 (Period...
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