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Article

Common genetic variations in CLOCK transcription factor are associated with nonalcoholic fatty liver disease.

World journal of gastroenterology - 21 Aug 2007

Sookoian Silvia, Castaño Gustavo, Gemma Carolina, Gianotti Tomas-Fernández, Pirola Carlos-Jose

Abstract excerpt

AIM: To investigate the role of gene variants and derived haplotypes of the CLOCK transcription factor in nonalcoholic fatty liver disease (NAFLD) and their relation with the disease severity. METHODS: A total of 136 patients with NAFLD and 64 healthy individuals were studied. Liver biopsy was performed in 91 patients. Six tag SNPs showing a minor allele frequency > 10% (rs1554483 C/G; rs11932595 A/G; rs4580704...

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Source

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Identifiers

PMID: 17696255
DOI: 10.3748/wjg.v13.i31.4242
PMCID: PMC4250625

Genes

CLOCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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