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Comparative genomics of Lbx loci reveals conservation of identical Lbx ohnologs in bony vertebrates

9 Jun 2008

Abstract excerpt

BACKGROUND: Lbx/ladybird genes originated as part of the metazoan cluster of Nk homeobox genes. In all animals investigated so far, both the protostome genes and the vertebrate Lbx1 genes were found to play crucial roles in neural and muscle development. Recently however, additional Lbx genes with divergent expression patterns were discovered in amniotes. Early in the evolution of vertebrates, two rounds of whole...

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PMID: 18541024
DOI: 10.1186/1471-2148-8-171

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