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Article

Elephant shark (Callorhinchus milii) provides insights into the evolution of Hox gene clusters in gnathostomes.

Proceedings of the National Academy of Sciences of the United States of America - 22 Sept 2009

Ravi Vydianathan, Lam Kevin, Tay Boon-Hui, Tay Alice, Brenner Sydney, Venkatesh Byrappa

Abstract excerpt

We have sequenced and analyzed Hox gene clusters from elephant shark, a holocephalian cartilaginous fish. Elephant shark possesses 4 Hox clusters with 45 Hox genes that include orthologs for a higher number of ancient gnathostome Hox genes than the 4 clusters in tetrapods and the supernumerary clusters in teleost fishes. Phylogenetic analysis of elephant shark Hox genes from 7 paralogous groups that contain all...

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Identifiers

PMID: 19805301
DOI: 10.1073/pnas.0907914106
PMCID: PMC2752591

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