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Article

Communication between the nucleotide site and the main molecular hinge of 3-phosphoglycerate kinase.

Biochemistry - 1 Jul 2008

Szabó Judit, Varga Andrea, Flachner Beáta, Konarev Peter V, Svergun Dmitri I, Závodszky Péter, Vas Mária

Abstract excerpt

3-Phosphoglycerate kinase is a hinge-bending enzyme with substrate-assisted domain closure. However, the closure mechanism has not been described in terms of structural details. Here we present experimental evidence of the participation of individual substrate binding side chains in the operation...

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Identifiers

PMID: 18540639
DOI: 10.1021/bi800411w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18540639-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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