Investigation of a functional quinine oxidoreductase (NQO2) polymorphism and cognitive decline.

doi:10.1016/j.neurobiolaging.2008.04.014

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Article

Investigation of a functional quinine oxidoreductase (NQO2) polymorphism and cognitive decline.

Neurobiology of aging - 1 Feb 2010

Payton Antony, Miyajima Fabio, Ollier William, Rabbitt Patrick, Pickles Andrew, Weiss Volkmar, Pendleton Neil, Horan Michael

Abstract excerpt

NAD(P)H dehydrogenase quinone 2 (NQO2) is a quinone reductase whose functions include the reduction of both oxidative stress during the redox cycle and neurotoxicity caused by the metabolism of catecholamines. We have investigated a functional non-synonymous exon 3 single nucleotide polymorphism (rs1143684) within the NQO2 gene for association with cognitive decline using a cohort of 722 community-dwelling older...

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PMID: 18538895
DOI: 10.1016/j.neurobiolaging.2008.04.014

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NQO2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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