Article
Dorsal interacting protein 3 potentiates activation by Drosophila Rel homology domain proteins.
Developmental and comparative immunology - 1 Jan 2008
Ratnaparkhi Girish S, Duong Hao A, Courey Albert J
Abstract excerpt
Dorsal interacting protein 3 (Dip3) contains a MADF DNA-binding domain and a BESS protein interaction domain. The Dip3 BESS domain was previously shown to bind to the Dorsal Rel homology domain. We show here that Dip3 also binds to the Relish Rel homology domain and enhances Rel family transcription factor function in both dorsoventral patterning and the immune response. While Dip3 is not essential, Dip3...
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