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Article

Tristetraprolin (TTP) gene polymorphisms in patients with rheumatoid arthritis and healthy individuals.

Modern rheumatology - 1 Jan 2008

Suzuki Takeshi, Tsutsumi Akito, Suzuki Hiroyuki, Suzuki Eiji, Sugihara Makoto, Muraki Yoshifumi, Hayashi Taichi, Chino Yusuke, Goto Daisuke, Matsumoto Isao, Ito Satoshi, Miyazawa Keiji, Sumida Takayuki

Abstract excerpt

Tristetraprolin (TTP) is an intracellular protein that modulates the production of cytokines, including TNFalpha, by binding to and destabilizing the mRNAs of these cytokines. Therefore, differences in TTP gene expression may affect the severity of inflammatory diseases, such as rheumatoid arthritis (RA). We searched for polymorphisms in the human TTP gene and for this purpose, we sequenced the entire TTP gene in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 18536977
DOI: 10.1007/s10165-008-0085-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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