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Signal control of hematopoietic stem cell fate: Wnt, Notch, and Hedgehog as the usual suspects

6 Jun 2008

Abstract excerpt

PURPOSE OF REVIEW: Hematopoietic homeostasis depends on appropriate self-renewal and differentiation capacity of hematopoietic stem cells. The characterization of the key extracellular signals that integrate with intracellular molecular machinery to regulate hematopoietic stem cells fate choice is crucial to move toward hematopoietic stem cell clinical application. RECENT FINDINGS: Several factors have been...

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Share to Hematopoietic Stem Cell Transplantation
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PMID: 18536569
DOI: 10.1097/moh.0b013e328303b9df

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