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Article

Expression of defective hepatitis B virus particles derived from singly spliced RNA is related to liver disease.

The Journal of infectious diseases - 15 Jul 2008

Soussan Patrick, Pol Jonathan, Garreau Florianne, Schneider Veronique, Le Pendeven Catherine, Nalpas Bertrand, Lacombe Karine, Bonnard Philippe, Pol Stanislas, Kremsdorf Dina

Abstract excerpt

BACKGROUND: Defective hepatitis B virus (HBV) particles, generated from singly spliced HBV RNA, have been detected in chronic carriers of HBV. The present study was designed to quantify the expression of defective HBV (dHBV) and wild-type HBV (wtHBV) genomes in the serum of patients with HBV infection and its relation to the severity of liver disease. METHODS: HBV and dHBV loads were determined by quantitative...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18532883
DOI: 10.1086/589623

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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