Article
Expression of defective hepatitis B virus particles derived from singly spliced RNA is related to liver disease.
The Journal of infectious diseases - 15 Jul 2008
Soussan Patrick, Pol Jonathan, Garreau Florianne, Schneider Veronique, Le Pendeven Catherine, Nalpas Bertrand, Lacombe Karine, Bonnard Philippe, Pol Stanislas, Kremsdorf Dina
Abstract excerpt
BACKGROUND: Defective hepatitis B virus (HBV) particles, generated from singly spliced HBV RNA, have been detected in chronic carriers of HBV. The present study was designed to quantify the expression of defective HBV (dHBV) and wild-type HBV (wtHBV) genomes in the serum of patients with HBV infe...
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