Article
Influence of hepatitis B virus (HBV) genotype on the clinical course of disease in patients coinfected with HBV and hepatitis delta virus.
The Journal of infectious diseases - 1 Jun 2009
Kiesslich Dagmar, Crispim Myuki Alfaia, Santos Carlos, Ferreira Fernando de Lima, Fraiji Nelson Abrahim, Komninakis Shirley Vasconcelos, Diaz Ricardo Sobhie
Abstract excerpt
OBJECTIVE: We evaluated the influence of hepatitis B virus (HBV) genotype on the course of disease in patients coinfected with HBV and hepatitis delta virus (HDV). METHODS: We evaluated HBV genotypes in 190 patients, 140 of whom had chronic HBV monoinfection and 50 of whom had chronic HBV-HDV coinfection. Real-time polymerase chain reactions for the amplification of HBV DNA and HDV RNA were developed, and we...
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