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Article

Differentiation of lethal and nonlethal, kor-regulated functions in the kilB region of broad host-range plasmid RK2.

Plasmid - 1 Jan 1991

Ayres E K, Saadi S, Schreiner H C, Thomson V J, Figurski D H

Abstract excerpt

In broad host-range plasmid RK2, several kil loci (kilA, kilB, kilC, kilE) and the replication initiator gene (trfA) are regulated by combination of kor determinants (korA, korB, korC, korE) in a regulatory network known as the kil-kor region. Although the kil determinants are not essential for replication, their coregulation with trfA suggests an involvement in plasmid maintenance or host-range. Plasmids...

Topics

Base Sequence
Cloning, Molecular
DNA Transposable Elements
Gene Expression Regulation, Bacterial
Genes, Regulator
Molecular Sequence Data
Mutation
Operon
Phenotype
Plasmids
Promoter Regions, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Replicon

Terminator Regions, Genetic

Transcription, Genetic

Transformation, Bacterial

Source

Identifiers

PMID: 1852017
DOI: 10.1016/0147-619x(91)90006-i

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1852017-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Differentiation of lethal and nonlethal, kor-regulated functions in the kilB region of broad host-range plasmid RK2.PMID 1852017Read ↗

Conjugative transfer functions of broad-host-range plasmid RK2 are coregulated with vegetative replication.Semantic proximity Read ↗

The kilA operon of promiscuous plasmid RK2: the use of a transducing phage (lambda pklaA-1) to determine the effects of the lethal klaA gene on Escherichia coli cells.Semantic proximity Read ↗

The partitioning activity of the RK2 central control region requires only incC, korB and KorB-binding site O(B)3 but other KorB-binding sites form destabilizing complexes in the absence of O(B)3.Semantic proximity Read ↗

Characterization of the growth inhibition phenotype of the kilAtelAB operon from IncP alpha plasmid RK2Ter.Semantic proximity Read ↗

Genes encoding the pKM101 conjugal mating pore are negatively regulated by the plasmid-encoded KorA and KorB proteins.Semantic proximity Read ↗

Co-operative interactions control conjugative transfer of broad host-range plasmid RK2: full effect of minor changes in TrbA operator depends on KorB.Semantic proximity Read ↗

Mutational and functional analysis of the korA and korB gene products of Streptomyces plasmid pIJ101.Semantic proximity Read ↗

Mutations in the gene encoding the replication-initiation protein of plasmid RK2 produce elevated copy numbers of RK2 derivatives in Escherichia coli and distantly related bacteria.Semantic proximity Read ↗

Mutations in the trfA replication gene of the broad-host-range plasmid RK2 result in elevated plasmid copy numbers.Semantic proximity Read ↗

Identification of a novel promoter in the replication control region of plasmid R6K.Semantic proximity Read ↗

A specific region in the N terminus of a replication initiation protein of plasmid RK2 is required for recruitment of Pseudomonas aeruginosa DnaB helicase to the plasmid origin.Semantic proximity Read ↗

Replication origin of the broad host range plasmid RK2. Positioning of various motifs is critical for initiation of replication.Semantic proximity Read ↗

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