Article
The 21bp repeat element of the human cytomegalovirus major immediate early enhancer is a negative regulator of gene expression in undifferentiated cells.
Nucleic acids research - 25 Apr 1991
Kothari S, Baillie J, Sissons J G, Sinclair J H
Abstract excerpt
The major immediate early regulatory region of human cytomegalovirus (HCMV) has a complex set of DNA sites through which both cellular and viral factors coordinately regulate immediate early gene expression. In undifferentiated human teratocarcinoma (T2) cells we have previously shown that major...
Topics
- Base Sequence
- Binding, Competitive
- Cell Differentiation
- Cytomegalovirus
- DNA, Viral
- Enhancer Elements, Genetic
- Gene Expression Regulation, Viral
- Genetic Vectors
- Humans
- Molecular Sequence Data
- Mutation
- Repetitive Sequences, Nucleic Acid
- Tumor Cells, Cultured