Article
Mapping the structural determinants of presynaptic neurotoxicity of snake venom phospholipases A2.
Toxicon : official journal of the International Society on Toxinology - 15 Jun 2008
Prijatelj Petra, Jenko Praznikar Zala, Petan Toni, Krizaj Igor, Pungercar Joze
Abstract excerpt
The structural features of presynaptically neurotoxic secretory phospholipases A(2) (sPLA(2)s) that are responsible for their potent and specific action are still a matter of debate. To identify the residues that distinguish a highly neurotoxic sPLA(2), ammodytoxin A (AtxA), from a structurally s...
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