Article
Genome-wide linkage analysis of a Parkinsonian-pyramidal syndrome pedigree by 500 K SNP arrays.
American journal of human genetics - 1 Jun 2008
Shojaee Seyedmehdi, Sina Farzad, Banihosseini Setareh Sadat, Kazemi Mohammad Hossein, Kalhor Reza, Shahidi Gholam-Ali, Fakhrai-Rad Hossein, Ronaghi Mostafa, Elahi Elahe
Abstract excerpt
Robust SNP genotyping technologies and data analysis programs have encouraged researchers in recent years to use SNPs for linkage studies. Platforms used to date have been 10 K chip arrays, but the possible value of interrogating SNPs at higher densities has been considered. Here, we present a genome-wide linkage analysis by means of a 500 K SNP platform. The analysis was done on a large pedigree affected with...
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