Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CC chemokine receptor 5 gene promoter activation by the cyclic AMP response element binding transcription factor

30 May 2008

Abstract excerpt

The chemokine receptor CCR5 is implicated in the pathogenesis of various inflammatory diseases, such as multiple sclerosis (MS), atherosclerosis, transplant rejection, and autoimmunity. In previous studies, we have shown that MS lesions are characterized by enhanced expression of transcription factors associated with stress responses, ie, IRF-1, NF-kappaB, and CREB-1, which modulate expression of both classes of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chemokine receptors and signaling
Share to interferon and immune responses
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18511806
DOI: 10.1182/blood-2008-01-135111

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CC chemokine receptor 5 gene promoter activation by the cyclic AMP response element binding transcription factorPMID 18511806Read ↗

IL-1β induction ofMUC5ACgene expression is mediated by CREB and NF-κB and repressed by dexamethasoneSemantic proximity Read ↗

NF-κB and Enhancer-binding CREB Protein Scaffolded by CREB-binding Protein (CBP)/p300 Proteins Regulate CD59 Protein Expression to Protect Cells from Complement AttackSemantic proximity Read ↗

Chemokine receptor CCR5 in interferon-treated multiple sclerosis.Semantic proximity Read ↗

CREB and phospho-CREB interact with RFX5 and CIITA to regulate MHC class II genes.Semantic proximity Read ↗

U5 Region of the Human Immunodeficiency Virus Type 1 Long Terminal Repeat Contains TRE-like cAMP-Responsive Elements That Bind both AP-1 and CREB/ATF ProteinsSemantic proximity Read ↗

Cyclin-Dependent Kinase 5 Differentially Regulates the Transcriptional Activity of the Glucocorticoid Receptor through Phosphorylation: Clinical Implications for the Nervous System Response to Glucocorticoids and StressSemantic proximity Read ↗

Interaction between CCAAT/enhancer binding protein and cyclic AMP response element binding protein 1 regulates human immunodeficiency virus type 1 transcription in cells of the monocyte/macrophage lineage.Semantic proximity Read ↗

Regulation of CCR5 expression and MIP-1alpha production in CD4+ T cells from patients with rheumatoid arthritis.Semantic proximity Read ↗

Regulation of mouse colony-stimulating factor-1 gene promoter activity by AP1 and cellular nucleic acid-binding protein.Semantic proximity Read ↗

Activation of the Interleukin-5 Promoter by cAMP in Murine EL-4 Cells Requires the GATA-3 and CLE0 ElementsSemantic proximity Read ↗

Repression of class II major histocompatibility complex genes by cyclic AMP is mediated by conserved promoter elements.Semantic proximity Read ↗

ETS1 transactivates the human GM-CSF promoter in Jurkat T cells stimulated with PMA and ionomycin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.