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Article

X-chromosome inactivation and skin disease.

The Journal of investigative dermatology - 1 Dec 2008

Sun Bryan K, Tsao Hensin

Abstract excerpt

X-chromosome inactivation (XCI) is the process in which females transcriptionally silence one of their two X chromosomes in early embryonic development, equalizing X chromosome gene expression between males and females. XCI depends on a gene called XIST, a functional RNA molecule that does not code for a protein. Recent studies indicate abundant intergenic transcription and nonprotein coding RNAs in the human...

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Share to Chromosomes, Human, X
Share to Epigenesis, Genetic
Share to Genome, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to RNA, Untranslated

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Share to Transcription, Genetic

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Source

Identifiers

PMID: 18509358
DOI: 10.1038/jid.2008.145

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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