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Article

Chemokine CXCL8 modulates GluR1 phosphorylation.

Journal of neuroimmunology - 31 Jul 2008

Catalano Myriam, Trettel Flavia, Cipriani Raffaela, Lauro Clotilde, Sobrero Fabrizia, Eusebi Fabrizio, Limatola Cristina

Abstract excerpt

The chemokine interleukin 8/CXCL8 induces the phosphorylation of the GluR1 subunit of the AMPA-type glutamate receptor in neurons and transfected HEK cells, on both serine 845 (S845) and 831 (S831) residues. We previously described that CXCL8 receptor CXCR2 and GluR1 co-precipitate and that GluR1/CXCR2 co-expression both in HEK cells and neurons impairs CXCL8-induced cell migration. Here we show that replacement...

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Source

Identifiers

PMID: 18508130
DOI: 10.1016/j.jneuroim.2008.04.017

Genes

CXCL8
CXCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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