Article
PKC anchoring to GluR4 AMPA receptor subunit modulates PKC-driven receptor phosphorylation and surface expression.
Traffic (Copenhagen, Denmark) - 1 Mar 2007
Gomes André R, Correia Susana S, Esteban José A, Duarte Carlos B, Carvalho Ana Luísa
Abstract excerpt
Changes in the synaptic content of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA)-type glutamate receptors lead to synaptic efficacy modifications, involved in synaptic plasticity mechanisms believed to underlie learning and memory formation. Early in development, GluR4 is highly expressed in the hippocampus, and GluR4-containing AMPA receptors are inserted into synapses. During synapse maturation,...
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