Article
Plasma HIV RNA decline and emergence of drug resistance mutations among patients with multiple virologic failures receiving resistance testing-guided HAART.
AIDS research and human retroviruses - 1 Jun 2008
Tozzi Valerio, Bellagamba Rita, Castiglione Filippo, Amendola Alessanda, Ivanovic Jelena, Nicastri Emanuele, Libertone Raffaella, D'Offizi Giampiero, Liuzzi Giuseppina, Gori Caterina, Forbici Federica, D'Arrigo Roberta, Bertoli Ada, Salvatori Maria Flora, Capobianchi Maria Rosaria, Antinori Andrea, Perno Carlo Federico, Narciso Pasquale
Abstract excerpt
Early recognition of virologic failure in patients with extensive drug resistance receiving salvage-HAART is essential to avoid exposure to subinhibitory regimens. We studied plasma viral load (PVL) decline and rates of drug-resistance mutation (DRM) accumulation in such patients. A prospective,...
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