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Article

K(ATP) channel polymorphism is associated with left ventricular size in hypertensive individuals: a large-scale community-based study.

Human genetics - 1 Jul 2008

Reyes Santiago, Terzic Andre, Mahoney Douglas W, Redfield Margaret M, Rodeheffer Richard J, Olson Timothy M

Abstract excerpt

ATP-sensitive K+ (K(ATP)) channel mutations have been identified in individuals with dilated cardiomyopathy and overt heart failure. Here, a common E23K functional polymorphism in the Kir6.2 channel pore versus cardiac phenotype was studied in a cross-sectional community-based cohort (n = 2,031)....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18504616
DOI: 10.1007/s00439-008-0519-3
PMCID: PMC2587318

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18504616-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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K(ATP) channel polymorphism is associated with left ventricular size in hypertensive individuals: a large-scale community-based study.PMID 18504616Read ↗

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