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Article

An IL-6 haplotype on human chromosome 7p21 confers risk for impaired renal function in type 2 diabetic patients.

Kidney international - 1 Aug 2008

Ng Daniel P K, Nurbaya Siti, Ye Sandra H J, Krolewski Andrzej S

Abstract excerpt

The human chromosome 7p21 locus harbors a major gene that influences variation of glomerular filtration rate and development of end-stage renal disease. The pro-inflammatory IL-6 cytokine is a candidate gene since chronic inflammation has been implicated in diabetic nephropathy and this gene is l...

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Identifiers

PMID: 18496509
DOI: 10.1038/ki.2008.202
PMCID: PMC2756185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18496509-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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