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Article

GABA regulates excitatory synapse formation in the neocortex via NMDA receptor activation.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 21 May 2008

Wang Doris D, Kriegstein Arnold R

Abstract excerpt

The development of a balance between excitatory and inhibitory synapses is a critical process in the generation and maturation of functional circuits. Accumulating evidence suggests that neuronal activity plays an important role in achieving such a balance in the developing cortex, but the mechanism that regulates this process is unknown. During development, GABA, the primary inhibitory neurotransmitter in...

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Identifiers

PMID: 18495889
DOI: 10.1523/JNEUROSCI.5599-07.2008
PMCID: PMC2684685

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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